Simon Oswell has performed and recorded as a soloist and chamber musician in Australia, Europe, South East Asia and the United States.

In California he occupied several principal viola positions, including the Carmel Bach Festival, Mozart Classical Orchestra and Hollywood Bowl Orchestra, and recorded for the motion picture industry. Since returning to Australia in 2006, Simon has appeared as principal viola with the Australian Romantic & Classical Orchestra, the Australian Chamber Orchestra, Melbourne, Adelaide, Tasmanian, Queensland Symphony Orchestras, Australian World Orchestra, and as chamber musician with Ensemble Liaison, Firebird Trio, Wilma and Friends, Quartz, Trio Dali, Ironwood, and the Australian Festival of Chamber Music.

Simon currently directs an annual chamber music school, in Clunes, Victoria.

Simon Oswell has performed regularly with the Australian Romantic & Classical Orchestra since 2016 and tutors at the Young Mannheim Symphonists education programs.